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MacsyDB databases

This website is the home of MacsyDB databases

The information presented here was originally obtained using the MacSyFinder program (or earlier prototypes of this program), eventually with some subsequent curation (check the literature references below).

It allows to query a dataset of protein secretion systems, conjugative and mobilization elements, and extracellular capsules retrieved from over 2000 complete genome sequences.

The profiles and models used are freely available in our website for systematic searches in the dedicated Galaxy web server (search for txsscan, conjscan, capsulefinder tools), or in the standalone version in conjunction with MacSyFinder and MacSyView (MacSyFinder and  MacSyView are also freely available on ). The documentation on these programs can be found at readthedocs.

References for citation purposes:

Secreton:

Abby SS, Rocha EPC (2012) The Non-Flagellar Type III Secretion System Evolved from the Bacterial Flagellum and Diversified into Host-Cell Adapted Systems. PLoS Genet 8(9): e1002983.

ConjDB:

Guglielmini, J. et al., Key components of the eight classes of type IV secretion systems involved in bacterial conjugation or protein secretion. (2014). Nucleic Acids Res., doi:10.1093/nar/gku194.

TXSSdb:

Abby SS, Cury J, Guglielmini J, Néron B, Touchon M, Rocha EPC. (2016) Identification of protein secretion systems in bacterial genomes. Scientific Reports. 16;6: 23080 doi:10.1038/srep23080.
 

CapsuleDB:

Olaya Rendueles, Marc Garcia-Garcerà, Bertrand Néron, Marie Touchon, Eduardo P. C. Rocha.  July 24, 2017 Abundance and co-occurrence of extracellular capsules increase environmental breadth: Implications for the emergence of pathogens doi:10.1371/journal.ppat.1006525.